Yes, general, and the biggest key for him is staying healthy, that's the thing I fear the most given his long history. Seems he can't go more than a year or two at most without something to sideline him, and it's my belief it is mostly because:
1. His relentless drive to win every point, every game, every match.
2. He plays so many tournaments, especially on slower hard courts that do the damage.
3. He goes deep in so many tournaments because he is a great player, which gives him less chance to recover.
So in a way, he is own worst enemy, but what can you do? He is only one man. You just can't win everything without it taking it's toll.
You may be able to do it for awhile when you are at your peak, but it definitely gets tougher as the years go by.
So that's why I say he might be better off not going deep in Miami. Also, I'd like him to play one less clay tournament, like Madrid.
That might give him a better chance to get to Wimbledon not so exhausted.
Respectfully,
masterclass